所有这些初步方案也许毫无效果。

All these initiatives may lead nowhere.

我试着减肥，但是毫无效果。

I tried losing weight, but nothing worked.

汽车的雨刷在瓢泼的大雨中几乎是毫无效果。

The car's windshield wipers were almost entirely ineffective against the sheets of rain.

“千真万确，”渡鸦哇哇地说道，“在房子里坚守到最后的人，传为美谈，但一向毫无效果。

"Very true, " croaked the Raven. "These last stands in a house make good stories, but nothing ever came of them.