现在你对此毫无办法。

There's nothing you can do about it now.

最好奇的人在她那种沉默面前，最顽强的人在她那种固执面前也都毫无办法。

The most curious were baffled by her silence and the most tenacious by her obstinacy.

亲爱的安妮：我希望您和您的读者可以给我提些建议，因为我实在是山穷水尽，毫无办法了。

Dear Annie: I hope you and your readers have some suggestions for me, because I'm just about at the end of my rope.

费迪南德和琼斯的防守并不够好，所以德赫亚对第52分钟克劳奇6码线上的头槌毫无办法。

Poor defensive marking by Rio Ferdinand and Phil Jones, however, left DE Gea exposed on 52 minutes when Crouch rose six yards out to head Matthew Etherington's corner into the net.