他终于痛切地认识到他犯了如此严重的错误。

Finally it came home sharply to him that he made such a serious mistake.

当时听完这句话，觉得有针刺了一下心脏，痛切心扉。

When listening to these words, I feel that needle a bit heart, poignant heart.

他的反感是如此痛切而敏锐，以致任何他可能看到或听到希刺克厉夫的地方他决不涉足。

So deep and sensitive was his aversion, that he refrained from going anywhere where he was likely to see or hear of Heathcliff.

这最后的观察看起来太真诚了，太痛切了，人们只能建议德波顿先生本人停止他孤独的奋斗，去大胆享受办公室生活的快乐了。

This last observation seems so heartfelt, so poignantly rendered, that one can only advise Mr DE Botton himself to cease his solitary endeavours and take the plunge into the pleasures of office life.