真格的，你到底去不去？

Seriously, are you going or not?

真格的，我不同意你的意见。

To tell the truth, I don't agree with you.

而其他被告则要面临真格的牢狱之灾。

Other defendants face actual prison terms.

我觉得所有的演员都真心喜欢这个理念——并不能够仅仅局限于荒诞滑稽的台词，还得在愚蠢之外动点真格的。

I think all the actors really liked that idea - that it wouldn't just be funny voices, that they get to do some real acting in addition to the silliness.

他就那么仰面躺在那里，头上冒着血，他最后看了我一眼，脸上的表情好像在说，老兄，至于嘛，咱们这又不是来真格的，对不对？

That is, there on his back, scalp bleeding, he gave, by shooting me a certain look, like, Dude, come on, we're not all that serious about this, are we?